Sonic & Knuckles (ソニック&ナックルズ Sonikku to Nakkuruzu?) is a 1994 platform video game in the Sonic the Hedgehog series for the Sega Genesis. It was developed in the United States at Sega Technical Institute by members of Sonic Team, and was published by Sega worldwide on October 18, 1994.

In addition to being a standalone game, through a system dubbed "lock-on technology," Sonic & Knuckles acts as an expansion pack to both Sonic the Hedgehog 2 and Sonic the Hedgehog 3, the latter with which it was developed in tandem.